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The new frontier in prenatal diagnosis
Panorama Test gives to pregnant women the opportunity to perform a prenatal screening, to evaluate chances of chromosomal fetal anomalies in a completely safe manner both for the mother-to-be and for the child.
It is a NIPT (Non-Invasive Prenatal Testing), a major modern evolution in prenatal screening methodology.
BIOTECHSOL is an authorized distributor of Natera’s Panorama™ non-invasive prenatal screening test in Italy. This website has not been reviewed by nor is it endorsed by Natera, Inc. BIOTECHSOL is solely responsible for maintaining the content on this website according to its Natera partnership guidelines as well as promotional guidelines in Italy.
The Test
Panorama Test detects the main trisomies, monosomies e microdeletions. The first two are also called aneuploidy, anomalies in the number of chromosomes. In a normal person the number of chromosomes is 46, divided into 23 pairs, while in these particular subjects there is one more (i.e. Trisomy) or less (i.e. Monosomy) chromosome.
What does it detect?
How accurate is it?
The accuracy of a screening test is its most important characteristic. Normal screening tests in use today have a margin of error that goes from 5% up to 15% (including either false positive, or false negative). This means that these tests can relate a fetal Trisomy risk to a pregnancy, in which the fetus is perfectly normal (false positive); or, on the other side, fail to detect a chromosomal anomaly in a fetus that is, indeed, affected (false negative). With the Panorama Test, the chances of false positives/negatives is reduced almost to zero.
How does it work?
During pregnancy, fragments of the fetus' DNA manage to pass through the placental barrier and enter the mother's bloodstream.These fragments are already detectable since the fifth week of gestation. The concentration of fetal DNA grows as the gestation progresses, until it disappears after birth. Thanks to this new and advanced technique it is possible, with a simple blood sample of the mother between the 10th and 12th week – when fetal DNA concentration in the bloodstream is optimal - to isolate such fragments for a chromosomal examination, ensuring a high sensitivity and specificity.
To whom is it addressed?
To all women in expectation, and especially:
